Technology
Solutions
AI + Robotics
OUR NEXT-GEN FORMULATION DEVELOPMENT PROCESS
1​
We start by onboarding a drug and determining solubility
2
We utilize our AI platform to make formulation predictions for a QTPP
3
Our robotic lab, builds and tests 1000s of formulations determined by our AI
4
​Data from our robotics trains our AI platform to predict the next set of formulations
5
Steps 2-4 repeat until the QTPP is met
6
​The top 3 formulations made this way are tested in animals
Our AI Capabilities
FORMULATION PREDICTION
We can determine the process parameters and excipients necessary to reach a QTPP
EXTRAPOLATION AND IN VIVO PREDICTION
Data from in vitro experiments can be used to
predict long term in vitro release as well as in vivo PK
MULTIVARIATE DATA ANALYSIS
Formulation experiments are complicated. Our tools help deconvolute data so you can determine next steps faster.
Our Automation Capabilities
PRECISE POWDER AND SOLVENT ADDITION
We've developed new tools for precise dosing of different solvents and powders
AUTOMATED SCHEDULING
Our robots carry out formulation processes automatically with custom
scheduling software
ONBOARD MICROFLUIDICS
Reduce the amount of drug used per run but still get results
DESIGNED FROM SCRATCH, FOR HIGH THROUGHPUT
Our instruments are designed for automation. We built them from the ground up using circuits, pumps, and solenoids
INTEGRATED PROCESS ANALYTICAL TECHOLOGY
Our robotic line has a lot of sensors ranging from Raman to absorbance and turbidity.
ULTIMATE DATA CAPTURE
Determine critical process parameters faster by combining sensor data with our AI capabilities
Critical process parameters
What process variables do you need to control? With what tolerance?
Critical quality attributes
What final product attributes lead to desired formulation characteristics?
Critical material attributes
What excipients can you utilize and what excipient properties should you be aware of?
Critical AI Insights
What's the impact on your formulation if one of these critical parameters changes?
Insights you can count on
KEY DELIVERABLES
Using our AI platform and high throughput robotic platform, you can perform a series of experiments and determine the key attributes and parameters that matter.
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AI Insights also help you analyze your data set to determine the answers to "what if" questions for root-cause analysis. ​​​​
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The Persist platform allows process engineers and formulation chemists to get a complete picture and supports them while they scale their formulation to commercial quantities.​​​