Services
Formulation Development
Let us do the thinking
End-to-end Formulation Development by Persist's Scientists
Persist utilizes AI-driven automation for formulation development. Let our scientists utilize our AI platform and our robotic laboratory to reach a QTPP.
Our scientists will design experiments, carry them out, analyze the data, and iterate using Persist's state of the art tools. We can also coordinate with outside CROs and CDMOs to carry out animal studies, write regulatory documentation, and more.
What We Do
FEASIBILITY STUDIES
High throughput experimentation using our robotics + AI platform to iteratively reach a QTPP in vitro. Includes analytical method development, formulation design and development, evaluation, and iteration.
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OPTIMIZATION
In vivo evaluation, PK/PD modeling and analysis, and iteration to translate in vitro results to in vivo results. Includes sterilization and stability studies
ANIMAL STUDIES & cGMP TRANSFER
Study design for in vivo evaluation, generation of GLP and cGMP batches with batch records, coordination with GLP labs for animal studies, and coordination with regulatory CROs for developing a package for IND submission
ADVANTAGES OF WORKING WITH PERSIST
30X
More Formulations
Test more variables in high throughput and arrive at a quality target product profile (QTPP) faster.
80%
Model Accuracy
Persist can develop an AI model based on drug-specific data that can be used for in vitro and in vivo optimization in silico after pre-screening in the lab
50%
Faster & Cheaper
Compared to a traditional R&D process, a combination of our AI + Robotics platform arrives at a QTPP 50% faster and offers incredible cost savings.
Case Studies: Other CROs vs. Persist
We've executed on dozens of projects successfully. Utilizing deep neural networks and generative AI models combined with custom robotics, solvent handling, and software designed for scheduling robotic processes, we've accelerated the pace of drug formulation time and time again.
#1: 6 MONTHS vs. 28 DAYS (Persist)
A customer spent 6 months optimizing the drug loading % of a 30 day long-acting injectable with another CRO. We built and optimized it with 60%+ drug loading within 28 days.
#2: 6 MONTHS vs. 14 DAYS (Persist)
A large pharma client asked us to develop a sustained release formulation for an extremely hydrophilic small molecule. Other CROs failed multiple times. Our scientists were able to meet QTPP within 14 days.
