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Research Scientist – Drug Product Development

Persist AI Company Overview

It takes 5 years for pharma to develop long acting drug injections for chronic diseases like cancer and diabetes. Persist uses AI-driven automation to reduce formulation development time down to 2 years, a ~50% reduction.

 

Job Overview

 

We are seeking a highly motivated and skilled scientist with an M.S. or Ph.D. in chemistry, biochemistry, organic chemistry, pharmaceutical sciences, or a related field to join our dynamic research team. The successful candidate will contribute to our ongoing efforts in pharmaceutical drug formulation, focusing on the development and optimization of novel drug delivery systems. The successful candidate will have experience in drug formulation development and/or
The position is on-site in West Sacramento, CA.

 

Job title:  Research Scientist

 

Department: Research and Development

Reports to: Director of R&D

 

Responsibilities

 

  • Formulation Development: Design and execute experiments to develop and optimize pharmaceutical drug formulations. Optimize, and scale up formulations to ensure consistent product quality and performance.

  • Analytical Testing: Utilize a variety of analytical techniques, (e.g., spectroscopy, chromatography, microscopy) to characterize drug formulations and assess their stability and performance.

  • Data Analysis and Interpretation: Analyze experimental data, interpret results, prepare reports, and make recommendations to guide formulation improvements and decision-making.

  • Collaboration: Work collaboratively with cross-functional teams, including chemists, pharmacologists, and regulatory affairs professionals, to integrate drug formulation efforts into broader drug development projects.

  • Literature Review: Stay up-to-date with industry developments and trends and apply knowledge to improve product formulations and development processes

  • Documentation: Prepare detailed and accurate documentation of experimental procedures, results, and conclusions for internal records and regulatory submissions.

  • Compliance: Ensure adherence to quality standards, safety protocols, and regulatory requirements in all aspects of drug formulation research.

 

Essential Qualifications (need to have)

 

  • Education: MS/PhD in Chemistry, Chemical Engineering, Pharmaceutical Sciences, Biochemistry, Biotechnology, or a related field, with a focus on drug formulation development.

  • Experience: Hands-on experience with pharmaceutical drug development or formulation development for small molecules and/or biologics

  • Technical Skills: Proficiency with experimental and analytical methods, techniques, and instrumentations (e.g., spectroscopy, HPLC, polymer chemistry, compound analysis, statistical analysis, assay development, experimental design). Solid understanding of the principles of drug formulation.

  • Regulatory Knowledge: Familiarity with GLP/GMP requirements for pharmaceutical development. Understanding of FDA regulatory guidelines.

  • Multidisciplinary Skills: Proficiency in interdisciplinary skills, including the ability to collaborate with experts in different scientific and engineering disciplines.

  • Communication Skills: Excellent written and verbal communication skills, with the ability to effectively convey complex scientific concepts to both technical and non-technical audiences.

  • Records Keeping: Attention to detail and ability to maintain accurate and detailed records.

  • Team Player: Demonstrated ability to work collaboratively in a team-oriented environment, fostering open communication and knowledge sharing.

  • Initiative: Proven ability to take initiative, drive projects independently, and adapt to evolving project goals and timelines. Ability to manage multiple projects and priorities simultaneously.

  • Adaptability: Demonstrated ability to adapt to new technologies, methodologies, and changes in project focus.

 

Preferred Qualifications (good to have)

 

  • Specialized Expertise: Demonstrated expertise in a specific area of drug formulation, such as nanoparticles, liposomes, or sustained-release systems, is desirable. Experience in other dosage forms such as oral solids or inhaled delivery systems is also valuable.

  • Technical Expertise: Previous experience using Powder XRD, SEM, CD (circular dichroism), DSC and/or Raman Spectroscopy is desirable.

  • Industry Experience: Previous experience working in the pharmaceutical or biotechnology industry, especially in early development settings or CMC. Experience in
    transferring developed formulations from the laboratory to larger-scale manufacturing processes.

  • Postdoctoral Experience: Additional postdoctoral experience in a relevant field, particularly with a focus on drug formulation or delivery systems

  • Project Leadership: Evidence of leading and managing research projects independently, including the ability to plan, execute, and deliver results within specified timelines.

  • Patent Experience: Experience in intellectual property management, including the filing of patents related to drug formulations or delivery systems.

  • Collaboration with External Partners: Experience in collaborating with external academic or industry partners to enhance research capabilities and explore collaborative opportunities.

 

Benefits 

 

  • Flexible working hours

  • Unlimited PTO and sick time

  • Certificate or license training reimbursement

  • Health benefits

  • Equity incentives

 

Equal Opportunity Employer

 

Persist AI is proud to be an equal-opportunity workplace. We are committed to equal employment opportunities regardless of race, color, religion, gender, age, national origin, disability, Protected Veteran status, gender, marital status, sexual orientation, or any other characteristic protected by federal, state, or local law.



Please send your resume/CV to HR@persist-ai.com

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